* Second-most points scored in a regular season game in NBA history: 81 (January 22, 2006).
* One of only two players in NBA history to score 80 points in a single game (the other is Wilt Chamberlain).
* One of only three players in NBA history to score 45-plus points per game for 4 consecutive games (the others are Elgin Baylor and Wilt Chamberlain), and the first to accomplish it since Chamberlain, who did it in November of 1964.
* Finished the month of January 2006 with a 13-game average of 43.4 points per game, the eighth highest in NBA history with the top seven all belonging to Chamberlain.
* Became the first player ever to outscore the opposing team through three quarters since the advent of the 24-second shot clock after scoring 62 points in three quarters of play on December 20, 2005 vs. the Dallas Mavericks.
* Scored 55 in one half (2nd half, January 22, 2006 vs. Toronto Raptors), matched the single-game high of the NBA's all-time leading scorer, Kareem Abdul-Jabbar
* eleven 50-point games in his career and 6 this season, both most among active players
* 35.2 PPG average is highest since Michael Jordan's 37.1 PPG average in 1988
*average 40+ PPG in a month (January 2006: 43.3 PPG, April 2006: 41,6 PPG), one of three players (other two: Wilt Chamberlain, Elgin Baylor)
*one of two players scoring 40+ PPG in a month more than once (other: Wilt Chamberlain)
* on his way to a 2,700-point season, which hasn't been done since Michael Jordan in 1990
* Scored 30 in one quarter (3rd quarter, December 20, 2005 vs. Dallas Mavericks), a Lakers' franchise record
* Scored 40+ points in 27 games, a Lakers' franchise record
* Scored 20+ points in 61 games, a Lakers' franchise record
* 18 field goals made in a half (2nd half, January 22, 2006 vs. Toronto Raptors), Lakers' franchise record
* 28 field goals attempted in a half (tied with Elgin Baylor; 2nd half, January 22, 2006 vs. Toronto Raptors), Lakers' franchise record
* 23 free throws made in a game (twice, most recently on January 31, 2006 vs. New York Knicks), Lakers' franchise record
* 62 consecutive free throws (January 11–22, 2006), Lakers' franchise record
* 7 three pointers without a miss (January 6, 2006 vs. Philadelphia 76ers), Lakers' franchise record
* 6 steals in a half (tied with 3 players; February 13, 2006 vs. Utah Jazz), Lakers' franchise record
* Most free throws made, one quarter: 14 (3rd quarter, December 20, 2005 vs. Dallas Mavericks; tied with 5 players).
* Most free throws attempted, one quarter: 16 (3rd quarter, December 20, 2005 vs. Dallas Mavericks; tied with 6 players).
* Greatest percentage of own team's point total (66.4% of the Lakers' 122 points vs. Toronto Raptors on January 22, 2006)
* Greatest percentage of both teams' combined point total (35.8% of the Lakers' and Raptors' 226 points on January 22, 2006)
* youngest to reach 15,000 points (27 years, 136 days), set January 6, 2006 vs. the Philadelphia 76ers.
* youngest to reach 16,000 points (27 years, 192 days), set March 3, 2006 vs. the Golden State Warriors.
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